Abstract Mutation in genes involved in DNA replication continuously disrupt DNA replication and give rise to genomic instability. a critical driver of oncogenesis. To prevent leukemia. immature T lymphocytes with genomic instability often undergo rapid cell death during development. https://iguanasellers.shop/product-category/mens-bag/
Mcm5 mutation leads to silencing of Stat1-bcl2 which accelerating apoptosis of immature T lymphocytes with DNA damage
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