Lungs are exposed to external oxidants from the environment as in harmful particles and smog. causing oxidative stress in the lungs and consequently respiratory ailment. The NF-E2-related factor 2 (Nrf2) is the one with transcriptional regulatory function. while its related protein Kelch-like ECH-associated protein 1 (Keap1) inhibits Nrf2 activity. https://www.hawtuoh.com/product-category/map/
The role of Keap1-Nrf2 signaling pathway in the treatment of respiratory diseases and the research progress on targeted drugs
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