Since their widespread use. pneumococcal conjugate vaccines (PCVs) have proven effective at reducing both invasive and noninvasive pneumococcal diseases and nasopharyngeal carriage of Streptococcus pneumoniae (Spn). To establish this level of protection. a three-dose schedule with a single booster (3 + 1) was the immunization regime in the USA. https://www.marcelovicente.com/product-category/shampoo-one/