Thioredoxin reductases are frequently overexpressed in various solid tumors as a protective mechanism against heightened oxidative stress. Inhibitors of this system. such as Auranofin. are effective in eradicating cancer cells. https://www.roomyroomers.shop/product-category/abstract-wall-art/
Inducing ubiquitination and degradation of TrxR1 protein by LW-216 promotes apoptosis in non-small cell lung cancer via triggering ROS production
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